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Mimi Mbegbu
Research Associate III

Starting from a pre-medical background, I received my bachelors in Biomedical Science, Chemistry, and Psychology from Northern Arizona University (NAU). Since graduating, I worked with labs of various backgrounds throughout the years and expanded my skill set. I am experienced in proteomics, molecular biology, Next Generation Sequencing methods, viral production, basic histology, and immunofluorescence. I now utilize these skills to assist the Barthel lab in achieving our goal of understanding the effects of telomere dysfunction on gene regulation and glioma formation.

I lived in Phoenix, Arizona for most of my life, but I love escaping to the woods of Flagstaff whenever I can. I enjoy stargazing, camping, gardening, PC games, petting dogs, and sleeping in until 11am on Saturdays. I am not the biggest fan of running or intense exercise, but I will happily take long walks around the city if food is involved.

Papers

Telomere Dysfunction in Human Astrocytes Drives Acrocentric Chromosome Instability and Nucleolar Reorganization Mbegbu et al. 2026. bioRxiv.

Haplotype-resolved genome assemblies of BJ and IMR-90 human fibroblast cell lines reveal extensive structural variation and enable reanalysis of historical sequencing data Ranallo-Benavidez et al. 2026. NAR.

Mapping the Telomeric 3D Interactome with Telomere-C Reveals Repetitive Element Hubs Associated with Telomere Maintenance Chen et al. 2025. bioRxiv.

Cell-Free DNA Sequencing Uncovers the Longitudinal Consequences of Temozolomide Treatment and Host Co-Culture in Glioblastoma Mankame et al. 2025. bioRxiv.

News

Four new manuscripts from the lab

Lab at ASHG 2025

Let's go Diamondbacks!

CSHL telomere meeting

One year anniversary lab lunch

Lab photos